Volumize. Rebuild. Renew. REGEN PDRN+ Crème is a first-of-its-kind volumizing crème that rebuilds visible fullness, firmness, and hydration, delivering Clinical Brightening results powered by Lira’s exclusive regenerative ingredient technology. How to use: Massage two pumps into clean skin, allowing product to fully absorb. Follow with appropriate Lira Clinical® serum, moisturizer, and/or SPF product.